Igor Branchi

Updated: 31.01.2024 


Delli Colli C, Chiarotti F, Campolongo P, Giuliani A, Branchi I (2024) Towards a network-based operationalization of plasticity for predicting the transition from depression to mental health. Nature Mental Health 2:200-208.

Branchi I, Viglione A, Vai B, Cirulli F, Benedetti F, Poggini S (2024) Breaking free from the inflammatory trap of depression: Regulating the interplay between immune activation and plasticity to foster mental health. Neuroscience Applied 3:103923.

Domschke K, ... , Branchi I et al. (2024) The definition of treatment resistance in anxiety disorders: a Delphi method-based consensus guideline. World psychiatry : official journal of the World Psychiatric Association 23:113-123.

Poggini S, Matte Bon G, Ciano Albanese N, Karpova N, Castren E, D'Andrea I, Branchi I (2024) Subjective experience of the environment determines serotoninergic antidepressant treatment outcome in male mice. Journal of affective disorders 350:900-908.

Branchi I (2023) A mathematical formula of plasticity: Measuring susceptibility to change in mental health and data science. Neuroscience and biobehavioral reviews 152:105272.

Delli Colli C, Borgi M, Poggini S, Chiarotti F, Cirulli F, Penninx B, Benedetti F, Vai B, Branchi I (2022) Time moderates the interplay between 5-HTTLPR and stress on depression risk: gene x environment interaction as a dynamic process. Translational psychiatry 12:274.

Branchi I (2022) Plasticity in mental health: A network theory. Neuroscience and biobehavioral reviews 138:104691.

Branchi I (2022) Recentering neuroscience on behavior: The interface between brain and environment is a privileged level of control of neural activity. Neuroscience and biobehavioral reviews 138:104678.

Benedetti F, Poletti S, Vai B, Mazza MG, Lorenzi C, Brioschi S, Aggio V, Branchi I, Colombo C, Furlan R, Zanardi R (2021) Higher baseline interleukin-1beta and TNF-alpha hamper antidepressant response in major depressive disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 42:35-44.

Branchi I, Giuliani A (2021) Shaping therapeutic trajectories in mental health: Instructive vs. permissive causality. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 43:1-9.

Branchi I, Poggini S, Capuron L, Benedetti F, Poletti S, Tamouza R, Drexhage HA, Penninx B, Pariante CM, European College of Neuropsychopharmacology ImmunoNeuroPsychiatry Thematic Working G, Marion L (2021) Brain-immune crosstalk in the treatment of major depressive disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 45:89-107.

De Picker LJ, Dias MC, Benros ME, Vai B, Branchi I, Benedetti F, Borsini A, Leza JC, Karkkainen H, Mannikko M, Pariante CM, Gungor ES, Szczegielniak A, Tamouza R, van der Markt A, Fusar-Poli P, Beezhold J, Leboyer M (2021) Severe mental illness and European COVID-19 vaccination strategies. The lancet Psychiatry 8:356-359.

Poggini S, Matte Bon G, Golia MT, Ciano Albanese N, Viglione A, Poleggi A, Limatola C, Maggi L, Branchi I (2021) Selecting antidepressants according to a drug-by-environment interaction: A comparison of fluoxetine and minocycline effects in mice living either in enriched or stressful conditions. Behavioural brain research 408:113256.

Vai B, Mazza MG, Delli Colli C, Foiselle M, Allen B, Benedetti F, Borsini A, Casanova Dias M, Tamouza R, Leboyer M, Benros ME, Branchi I, Fusar-Poli P, De Picker LJ (2021) Mental disorders and risk of COVID-19-related mortality, hospitalisation, and intensive care unit admission: a systematic review and meta-analysis. The lancet Psychiatry 8:797-812.

Vinkers CH, van Amelsvoort T, Bisson JI, Branchi I, Cryan JF, Domschke K, Howes OD, Manchia M, Pinto L, de Quervain D, Schmidt MV, van der Wee NJA (2020) Stress resilience during the coronavirus pandemic. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 35:12-16.

Golia MT, Poggini S, Alboni S, Garofalo S, Ciano Albanese N, Viglione A, Ajmone-Cat MA, St-Pierre A, Brunello N, Limatola C, Branchi I, Maggi L (2019) Interplay between inflammation and neural plasticity: Both immune activation and suppression impair LTP and BDNF expression. Brain, behavior, and immunity 81:484-494.

Poggini S, Golia MT, Alboni S, Milior G, Sciarria LP, Viglione A, Matte Bon G, Brunello N, Puglisi-Allegra S, Limatola C, Maggi L, Branchi I (2019) Combined Fluoxetine and Metformin Treatment Potentiates Antidepressant Efficacy Increasing IGF2 Expression in the Dorsal Hippocampus. Neural Plast 2019:4651031.

Viglione A, Chiarotti F, Poggini S, Giuliani A, Branchi I (2019) Predicting antidepressant treatment outcome based on socioeconomic status and citalopram dose. Pharmacogenomics J 19:538-546.

Carhart-Harris RL, Roseman L, Haijen E, Erritzoe D, Watts R, Branchi I, Kaelen M (2018) Psychedelics and the essential importance of context. J Psychopharmacol:269881118754710.

Alboni S, van Dijk RM, Poggini S, Milior G, Perrotta M, Drenth T, Brunello N, Wolfer DP, Limatola C, Amrein I, Cirulli F, Maggi L, Branchi I (2017) Fluoxetine effects on molecular, cellular and behavioral endophenotypes of depression are driven by the living environment. Mol Psychiatry 22:552-561.

Chiarotti F, Viglione A, Giuliani A, Branchi I (2017) Citalopram amplifies the influence of living conditions on mood in depressed patients enrolled in the STAR*D study. Transl Psychiatry 7:e1066.

Alboni S, Poggini S, Garofalo S, Milior G, El Hajj H, Lecours C, Girard I, Gagnon S, Boisjoly-Villeneuve S, Brunello N, Wolfer DP, Limatola C, Tremblay ME, Maggi L, Branchi I (2016) Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment. Brain, behavior, and immunity.

Bisht K, Sharma KP, Lecours C, Sanchez MG, El Hajj H, Milior G, Olmos-Alonso A, Gomez-Nicola D, Luheshi G, Vallieres L, Branchi I, Maggi L, Limatola C, Butovsky O, Tremblay ME (2016) Dark microglia: A new phenotype predominantly associated with pathological states. Glia 64:826-839.

Branchi I, Alboni S, Maggi L (2014) The role of microglia in mediating the effect of the environment in brain plasticity and behavior. Front Cell Neurosci 8:390.

Branchi I, Cirulli F (2014) Early experiences: Building up the tools to face the challenges of adult life. Dev Psychobiol 56:1661-1674.

Branchi I, Curley JP, D'Andrea I, Cirulli F, Champagne FA, Alleva E (2013a) Early interactions with mother and peers independently build adult social skills and shape BDNF and oxytocin receptor brain levels. Psychoneuroendocrinology 38:522-532.

Branchi I, Santarelli S, Capoccia S, Poggini S, D'Andrea I, Cirulli F, Alleva E (2013b) Antidepressant treatment outcome depends on the quality of the living environment: a pre-clinical investigation in mice. PLoS One 8:e62226.

Branchi I, Santarelli S, D'Andrea I, Alleva E (2013c) Not all stressors are equal: Early social enrichment favors resilience to social but not physical stress in male mice. Horm Behav 63:503-509.

Branchi I (2011) The double edged sword of neural plasticity: Increasing serotonin levels leads to both greater vulnerability to depression and improved capacity to recover. Psychoneuroendocrinology 36:339-351.

Branchi I, Karpova NN, D'Andrea I, Castren E, Alleva E (2011) Epigenetic modifications induced by early enrichment are associated with changes in timing of induction of BDNF expression. Neurosci Lett 495:168-172.

Branchi I, D'Andrea I, Cirulli F, Lipp HP, Alleva E (2010) Shaping brain development: mouse communal nesting blunts adult neuroendocrine and behavioral response to social stress and modifies chronic antidepressant treatment outcome. Psychoneuroendocrinology 35:743-751.

Branchi I (2009) The mouse communal nest: investigating the epigenetic influences of the early social environment on brain and behavior development. Neuroscience and biobehavioral reviews 33:551-559.

Branchi I, D'Andrea I, Armida M, Cassano T, Pezzola A, Potenza RL, Morgese MG, Popoli P, Alleva E (2008) Nonmotor symptoms in Parkinson's disease: investigating early-phase onset of behavioral dysfunction in the 6-hydroxydopamine-lesioned rat model. J Neurosci Res 86:2050-2061.

D'Andrea I, Alleva E, Branchi I (2007) Communal nesting, an early social enrichment, affects social competences but not learning and memory abilities at adulthood. Behavioural brain research 183:60-66.

Branchi I, D'Andrea I, Fiore M, Di Fausto V, Aloe L, Alleva E (2006) Early social enrichment shapes social behavior and nerve growth factor and brain-derived neurotrophic factor levels in the adult mouse brain. Biol Psychiatry 60:690-696.